Mold Glossary
Absidia
A zygomycete fungus. Reported to be allergenic. May cause mucorosis in immune
compromised individuals. The sites of infection are the lung, nasal sinus,
brain, eye and skin. Infection may have multiple sites.
Acremonium(Cephalosporium)
Reported to be allergenic. Can produce a trichothecene toxin that is toxic
if ingested. It was the primary fungus identified in at least two houses
where the occupant complaints were nausea, vomiting and diarrhea. Asexual
state of Emericellopsis sp., Chaetomium sp., and Nectripsis sp.
It can produce mycetomas, infections of the cornea and nails.
Alternaria
Aw - 0.89. Conidia dimensions: 18-83 x 7-18 microns. This
is one of the main fungal causes of allergy, being a common
type I (ex.: hay fever, asthma) & type III (ex.: hypersensitivity
pneumonitis) allergen. The large spore size suggests
that this fungus will settle in the nose, mouth, and upper
respiratory tract, causing nasal septum infections. Alternaria is
a common cause of extrinsic asthma, with acute symptoms including
edema and bronchiospasms; chronic cases may develop pulmonary
emphysema. “Baker’s asthma” is commonly
associated with inhalation of Alternaria conidia
present in flour. Other diseases caused by this mold
include: “farmer’s lung”, “woodworker's
lung”, “apple store hypersensitivity”,
mycotic keratitis (fungal infection of the cornea), nasal
lesions, subcutaneous lesions, skin infections, nail infections,
and osteomyelitis (inflammation of the bone). [It should
be noted that most of the reported infections affected persons
with underlying disease or those taking immunosuppressive
drugs.]
Toxic metabolites (that may cause disease in humans) produced
by these microbes include AME (alternariol monomethylether),
tenuazonic acid, and altertoxins (which are mutagenic). Several
species are pathogenic to plants, and some are processed
for use in the biocontrol of weeds and other plants. A.
alternata produces alternariol, an antifungal metabolite.
Alternaria is commonly found indoors in dust, carpeting,
textiles, on foodstuffs, and horizontal surfaces (such as
window frames). It has also been isolated from substrates
such as sewage, leather, stone monuments, optical instruments,
cosmetics, computer disks, and even jet fuel. Outdoors,
it may be found on dead organic debris, seeds, plants (and
can contribute to the spoilage of agricultural products),
in soil, and air--one of the reasons that it is a widespread
genus. Alternaria conidia are easily carried
by the wind, with peak air concentrations occurring in the
summer and early fall. Colonies grow fast, are suede-like
to floccose, and black to olivaceous-black or grayish in
color.
amerospore
A spherical or oval single-celled fungal spore that is
practically unidentifiable by itself. Genera with
this type of spore include, but are not limited to, Aspergillus, Penicillium,
and Trichoderma.
For example, Penicillium is
easily identifiable when sampling
using culturing techniques. However,
when sampling with non-culturing
techniques, such as spore traps or
tape-lifts, the free spores with
no remnants of the fungal structure
are indistinguishable from Aspergillus and
various other genera that also produce
small round and oval spores with
little or no pigmentation. Due to
this fact, Penicillium will often
be categorized on laboratory reports
in an "amerospore" and/or "Aspergillus/Penicillium" group.
Arthrinium
Widespread saprophyte found on decomposing plant material,
particularly grasses, and on soil. It is a white, fuzzy mold.
It should be considered to be an allergen. This fungus has
also been documented in various subcutaneous infections.
No diseases related to toxic effects have been recorded to
date.
ascospore
A spore borne in a special cell called an ascus. Spores
of this type are reported to be allergenic.
All ascomycetes, members of a group of fungi called Ascomycotina, have this
type of spore. The minute black dots on rotting wood and leaves or the little
cups on lichens are examples of ascomycetes; another is the "truffle" mushroom.
Aspergillus
caesiellus
This species is only occasionally pathogenic.
Aspergillus
candidus
Aw 0.75. Conidia dimensions: 2.5-4 microns. Found
in warm soils, grain and in the secondary decay of vegetation.
Associated with respiratory complaints in a recent house
investigation. Can produce the toxin petulin that may be
associated with disease in humans and other animals.
Aspergillus
carneus
This species is only occasionally pathogenic.
Aspergillus
clavatus
Conidia
dimensions: 3-4.5 x 2.5-4.5 microns. Found in soils and animal
manure.
Can produce the toxin petulin that may be associated with disease in humans
and other animals. This species is only occasionally pathogenic.
Aspergillus
deflectus
This
species is only occasionally pathogenic.
Aspergillus
flavus
Aw 0.78. Conidia dimensions: 3-6 microns or 3-5 microns.
It grows on moldy corn and peanuts. It can be found in warm
soil, foods and dairy products. Some strains are capable of
producing a group of mycotoxins- in the aflatoxin group. Aflatoxins
are known animal carcinogens. There is limited evidence to
suggest that this toxin is a human carcinogen. The toxin is
poisonous to humans by ingestion. It may also result in occupational
disease via inhalation. Experiments have indicated that it
is teratogenic and mutagenic. It is toxic to the liver. It
is reported to be allergenic. Its presence is associated with
reports of asthma. It can be found in water-damaged carpets.
The production of the fungal toxin is dependent on the growth
conditions and on the substrate used as a food source. This
fungus is associated with aspergillosis of the lungs and/or
disseminated aspergillosis. This fungus is occasionally identified
as the cause of corneal, otomycotic and nasoorbital infections.
Aspergillus fumigatus
Aw 0.82; Optimum> 0.97. Conidia dimensions: 2-3.5 microns. Considered a
human pathogen, this organism causes both allergic aspergillosis and invasive
aspergillosis (invasive aspergillosis usually affects individuals who are immune
compromised). It is commonly found outdoors on cereal grains, in cool to warm
soils, and in compost piles (even with temperatures exceeding 40 degrees C).
Aspergillus
glaucus
Conidia dimensions: 5-6.5 microns. Common outdoor fungus
in the winter. It is reported to be allergenic. This species
is only occasionally pathogenic. It can grow on leather. This
fungus can grow at low moisture levels on grains, sugary food
products, meat and wool. The ascomycetous state is Eurotium sp.
Aspergillus
nidulans
Aw
0.78. Conidia dimensions: 2-4 microns. Found in mild to warm
soils and on slowly decaying plants. Can produce the mycotoxin
sterigmatocystin. This toxin has been shown to produce liver
and kidney damage in lab animals. This fungus is associated
with aspergillosis of the lungs and/or disseminated aspergillosis.
This species is only occasionally pathogenic.
Aspergillus
niger
Aw
0.77; Optimum> 0.97. Conidia dimensions: 3.5 - 5 microns
or 4 to 5 microns. Less common cause of aspergillosis. It has
a musty odor. It is commonly found in the environment on textiles,
in soils, grains, fruits and vegetables. It has been reported
to cause skin and pulmonary infections. It is a common cause
of fungal related ear infections, including otomycosis.
Aspergillus
ochraceus
Aw 0.77. Conidia dimensions: 2.5 - 3 microns. Found
in grains, soil and salted food products. It is not usually
associated with decaying vegetation. Can produce a kidney toxin
ochratoxin A that may produce ochratoxicosis in humans. This
is also known as Balkan nephropathy. The toxin is produced
at optimum growth conditions at 25 degrees C and high moisture
conditions. The ochratoxin may also be produced by other Aspergillus sp. and Penicillium sp. Other
toxins that can be produced by this fungus include penicillic
acid, xanthomegnin and viomellein. These are all reported to
be kidney and liver toxins.
Aspergillus
oryzae
This
species is only occasionally pathogenic.
Aspergillus
parasiticus
Some strains are capable of producing a group of mycotoxins-
in the aflatoxin group. Aflatoxins are known animal carcinogens.
There is limited evidence to suggest that this toxin is a human
carcinogen. The toxin is a poisonous to humans by ingestion.
Experiments have indicated that it is teratogenic and mutagenic.
It is toxic to the liver. The production of the fungal toxin
is dependent on the growth conditions and on the substrate
used as a food source.
Aspergillus/Penicillium-Like
This category is included on laboratory analysis reports for air samples containing
certain free spores without other identifying structures. The free
spores of Aspergillus and Penicillium (and other genera
with small, round or ovoid, and colorless spores) are essentially indistinguishable,
using standard microscopic examination methods.
If required, cultured specimens can provide additional characteristics
that will enable technicians to determine what genus is represented.
If sporulating structures are present, Aspergillus is
readily identifiable on tape samples. [Discovery of the Aspergillus species
requires the culture of the fungus under different conditions
of media, humidity, and temperature. Identifying Penicillium species
is difficult, but, in some cases, possible.]
These two allergenic molds are among those most often found
in contaminated buildings. Aspergillus is represented
by numerous species, many of which produce toxic substances.
It may be associated with symptoms such as sinusitis, allergic
bronchiopulmonary aspergillosis, and other allergic symptoms.
As if not to be outdone, Penicillium too is found in
increased numbers in interiors. Some of its many species produce
toxic substances that can cause allergic reactions, mucous
membrane irritation, headaches, vomiting, and diarrhea.
Aspergillus
penicilloides
Conidia
dimensions: 3-3.5 x 4-5 microns. Can grow in areas with low
water activity. It is found in house dust and food.
Aspergillus
restrictus
This
species is only occasionally pathogenic.
Aspergillus
Aw 0.75 - 0.82. Reported to be allergenic. Members of this
genus are reported to cause ear infections. Many species produce
mycotoxins that may be associated with disease in humans and
other animals. Toxin production is dependent on the species
or a strain within a species and on the food source for the
fungus. Some of these toxins have been found to be carcinogenic
in animal species. Several toxins are considered potential
human carcinogens. Common cause of extrinsic asthma (immediate-type
hypersensitivity: type I). Acute symptoms include edema and
bronchiospasms; chronic cases may develop pulmonary emphysema;
may also be associated with sinusitis, allergic bronchiopulmonary
aspergillosis, and other allergic symptoms.
Aspergillus
sydowi
This
species is only occasionally pathogenic.
Aspergillus
terreus
Aw 0.78. Conidia dimensions: 1.8-2.4 microns or 2 -
2.5 microns. Aleurospores 6 - 7 microns in diameter are also
produced. Found in warmer soil and in grains, straw, cotton
and decomposing vegetation. Can produce the toxin patulin and
citrinin that may be associated with disease in humans and
other animals. This fungus is associated with aspergillosis
of the lungs and or disseminated aspergillosis. Found as an
isolate from otomycosis - ear infection, and onychomycosis
- infection of finger or toenails.
Aspergillus
ustus
This
species is only occasionally pathogenic.
Aspergillus
versicolor
Aw
0.78. Conidia dimensions: 2-3.5 microns. Mostly in temperate
zones, it is commonly found in air, house dust, foods (including
dairy products), soil, hay, and cotton. It sometimes produces
the mycotoxin "sterigmatocystin", which can cause
diarrhea and upset stomach, and is a possible carcinogen, affecting
the liver and kidneys. Various other toxins are associated
with A. versicolor, such as aspercolorin, averufin,
cyclopiazonic acid, and versicolorin. Additionally, the volatile
organic compound (VOC) "geosmin" is generated by
the action of this mold. Often an irritant to mucus membranes
of humans and pets, geosmin has a musty, earthy odor.
Aureobasidium
Found in soil, forest soils, fresh water, aerial portion
of plants, fruit, marine estuary sediments, wood. Allergen,
Type I allergies (hay fever, asthma). Type III hypersensitivity
pneumonitis: "humidifier fever", "sauna taker's
lung". Growth indoors is widespread where moisture accumulates-
especially bathrooms and kitchens- on shower curtains, tile
grout, windowsills, textiles, liquid waste materials. Potential
toxic production is not known. Rare reports of: isolates from
skin lesions, keratitis, spleen abscess in a lymphoma patient,
blood isolate from a leukemic patient.
Basidiomycetes
Taxonomic designation for fungi of the subdivision "Basidiomycotina",
which includes mushrooms and puffballs. They produce spores that are formed
on the outside of a special cell, called the "basidium".
basidiospore
An exogenous sexual spore (meiospore) borne on a basidium. Or, a spore from
a basidiomycete (a member of Basidiomycetes). Many varieties are reported
to be allergenic.
Bipolaris
A fungus with large spores that could be expected to be
deposited in the upper respiratory tract. This fungus can produce
the mycotoxin - sterigmatocystin, which has been shown to produce
liver and kidney damage when ingested by laboratory animals.
Blastomyces
Human pathogen. The fungus is commonly found in soil. It
is a dimorphic fungus that has filamentous fungus when grown
at 25 degrees C. and a yeast form at 37 degrees C.
Botrytis
Aw 0.93.
Conidia dimensions: 7-14 x 5-9 microns. It is parasitic on
plants and soft fruits. Found in soil and on house plants and
vegetables, it is also known as "gray mold". It causes
leaf rot on grapes, strawberries, lettuce, etc. It is a well-known
allergen, producing asthma type symptoms in greenhouse workers
and the symptoms of "wine grower's lung".
Candida
Part of the normal flora of mouth and other mucous membranes
in the body. Thrush and other diseases caused by Candida
albicans usually occur after prolonged treatment with antibiotics
or steroids. The environment is not a likely source of exposure
for this fungus. Cells from the organism are usually not airborne.
Reported to be allergenic.
Cephalosporium
See Acremonium
Chaetomium
Large ascomycetous fungus producing perithecia. It is found
on a variety of substrates containing cellulose, including
paper and plant compost. It has been found on paper in sheetrock.
It can produce an Acremonium-like state on fungal media.
Varieties are considered allergenic and have been associated
with peritonitis, cutaneous lesions, and system mycosis.
Cladosporium
fulvum (Fulvia fulva)
Conidia dimensions: 12-47 x 4-10 microns. It is found on the leaves of tomatoes.
Cladosporium
herbarum
Aw
0.88. Conidia dimensions: 5-23 x 3-8 microns. It is found on
dead plants, woody plants, food, straw, soil, paint and textiles.
Cladosporium
macrocarpum
Conidia
dimensions: 9-29 x 5-13 microns. It is found on dead plants,
woody plants, food, straw, soil, paint, and textiles.
Cladosporium (Hormodendrum)
Aw 0.88;
Aw 0.84. Most commonly identified outdoor fungus. The outdoor
numbers are reduced in the winter. The numbers are often high
in the summer. Often found indoors in numbers less than outdoor
numbers. It is a common allergen. Indoor Cladosporium sp.
may be different than the species identified outdoors. It is
commonly found on the surface of fiberglass duct liners in
the interior of supply ducts. A wide variety of plants are
food sources for this fungus. It is found on dead plants, woody
plants, food, straw, soil, paint, and textiles. Produces greater
than 10 antigens. Antigens in commercial extracts are of variable
quality and may degrade within weeks of preparation. Common
cause of extrinsic asthma (immediate-type hypersensitivity:
type I). Acute symptoms include skin lesions, eye ulceration,
mycosis (including onychomycosis, an infection of the nails
of the feet or hands) edema and bronchiospasms; chronic cases
may develop pulmonary emphysema.
Cladosporium
sphaerospermum
Conidia
dimensions: 3-4.5 microns. It is found as a secondary invader
of plants, food, soil, paint and textiles.
conidium
A thin-walled,
asexual spore borne exogenously on an often specialized hypha
(conidiophore) and is deciduous at maturity. (plural form:
conidia.)
conidia,
unidentified
These are mold spores that do not show morphological characteristics
that allow identification. Because there are tens of thousands
of types of fungi, many fall into the "other" or "unknown" category.
If they are present in significant numbers, additional measures
can be taken to identify them. When spore counts are listed
in the category: "Unidentified Conidia" their numbers
are considered "normal".
Conidobolus
Can cause
a chronic inflammatory disease of the nasal mucosa (entomophthoromycosis).
Cryptococcus neoformans
A basidiomycetous encapsulated fungal organism found
worldwide, mainly around pigeon roosts and soil contaminated
with decaying pigeon or chicken droppings. It is generally
accepted that the organism enters the host by the respiratory
route in the form of a dehydrated haploid yeast or as basidiospores.
Hematogenously spreading to extrapulmonary tissues, its predilection
for the brain means infected persons usually contract meningoencephalitis,
which can be fatal.
Cryptostroma
corticale
Conidia
dimensions: 4-6.5 x 3.5-4 microns. Found on the bark of maple
and sycamore trees and on stored logs.
Cunninghamella
Can cause
disseminated and pulmonary infections in immune compromised
hosts.
Curvularia
Reported to be allergenic and has been associated with
allergic fungal sinusitis. It may cause corneal infections,
mycetoma, and infections in immune compromised hosts.
Dictyosporium
A fungal genus of the classification group "Hyphomycetes".
At this time, there is no information available concerning Dictyosporium allergenicity
or toxicity, but as a member of the classification group "Dematiaceous
Hyphomycetes", it could potentially cause phaeohyphomycosis
(see phaeohyphomycosis). It is found in terrestrial
and freshwater habitats, and is a common saprobe of submerged
lignocellulose substances. The microscope reveals its spores
to be multicellular and tongue-shaped; with subconcentric cells.
Colonies may appear dark brown, green-black, or black.
Dreschlera
Conidia dimensions: 40-120 x 17-28 microns. Found on grasses,
grains and decaying food. It can occasionally cause a corneal
infection of the eye.
Epicoccum
Conidia
dimensions: 15-25 microns. A common allergen. It is found in
plants, soil, grains, textiles and paper products.
Epidermophyton
Can cause
infections of skin (including ringworm) and nails.
fungus
Neither animals nor plants, these saprophytic and parasitic spore-producing
organisms rate a taxonomic kingdom of their own. Fungi include molds, rusts,
mildews, smuts, mushrooms, puffballs, and yeasts. It is estimated that more
than 1.5 million species of fungi exist.
Fusarium
solani
Aw 0.90. Macroconidia dimensions: 27-52 x 4.4-6.8;
Microcondia dimensions: 8-16 x 2-4 microns. Found in plants
and soils. Can produce trichothecene toxins that may be associated
with disease in humans and animals.
Fusarium
Aw 0.90. A common soil fungus. It is found on a wide range
of plants. It is often found in humidifiers. Several species
in this genus can produce potent trichothecene toxins. The
trichothecene (scirpene) toxin targets the following systems:
circulatory, alimentary, skin, and nervous. Produces vomitoxin
on grains during unusually damp growing conditions. Symptoms
may occur either through ingestion of contaminated grains or
possibly inhalation of spores. The genera can produce hemorrhagic
syndrome in humans (alimentary toxic aleukia). This is characterized
by nausea, vomiting, diarrhea, dermatitis, and extensive internal
bleeding. Reported to be allergenic. Frequently involved in
eye, skin, and nail infections.
Geotrichum
Aw 0.90. Conidia dimensions: 6-12 x 3-6 microns. Aw 0.90.
A common contaminant of grains, fruits, dairy products, paper,
textiles, soil, and water; often present as part of the normal
human flora. The species Geotrichum candidum can cause
a secondary infection (geotrichosis) in association with tuberculosis.
This rare disease can cause lesions of the skin, bronchi, mouth,
lung, and intestine.
Gliocladium
A fungus that is structurally similar to Penicillium sp.
It is reported to be allergenic.
Helicomyces
A mitosporic mold often encountered on decaying plant
matter. The genus name prefix "helico" is derived
from the shape of the mold's microscopic structure; certain
filaments (sometimes the conidia) curve into a helical path.
Reported effects upon human health in the indoor
environment are not available at this time.
Scientists have shown the interaction of Helicomyces
roseus with nitrogen-fixing bacteria to be a vital component
of an effective soil enriching system (where sugar cane litter
is the decomposition target). Helicomyces lilliputeus has
long been known as an important sewage treatment systems
decomposer, so it is not unexpected that other members of
this genus have been observed living on wood submerged in
water.
Helminthosporium
Reported to be allergenic.
Histoplasma
A fungus that has filamentous growth at 25 degrees C. and
yeast growth at 37 degrees C. It is reported to be a human
pathogen. It may be associated with birds.
Humicula
Grows
on products with a high cellulose
content. These fungi are also found in soil and on plant debris.
hyaline
mycelia
Mycelia that are transparent,
translucent, or colorless. If no
reproductive structures are present,
identification is difficult. Often
associated with allergic symptoms.
Memnoniella
A cellulolytic
fungus that is very closely related to Stachybotrys sp.
Both fungi have a worldwide distribution and are often found
together and are commonly found in soil. Recent studies on
mycotoxins revealed that Memnoniella echinata can
have a toxicity similar to that of some isolates of Stachybotrys
chartarum. Both produce varying amounts of simple trichothecenes.
Thus, it is suggested that Memnoniella sp. should
also be considered potentially dangerous in indoor air. The
major difference between the two fungi is that the conidia
of Memnoniella sp. are in long persistent chains while
those of Stachybotrys are aggregated in slimy heads.
Also the aerodynamic diameter of Memnoniella sp. conidia
is smaller and it would be expected to have an even greater
potential to penetrate deep into lungs than the conidia of Stachybotrys sp.
Microsporum
Causes
ringworm in humans.
mold
Molds are a group of organisms that belong to the taxonomic kingdom of Fungi.
There are over 20,000 species of mold. Molds reproduce by making spores.
Mold spores waft through the indoor and outdoor air continually. When mold
spores land on a damp spot indoors, they may begin growing and digesting
whatever they are growing on. Molds can grow on virtually any organic substance,
as long as moisture and oxygen are present.
Monilia
Reported
to be allergenic. This fungus produces soft rot of tree fruits.
Other members produce a red bread mold. It is infrequently
involved in corneal eye infections.
Mucor
Often found in soil, dead plant material, horse dung, fruits
and fruit juice. It is also found in leather, meat, dairy products,
animal hair, and jute. A Zygomycetes fungus that may be allergenic
(skin and bronchial tests). This organism and other Zygomycetes
will grow rapidly on most fungal media. May cause mucorosis
in immune compromised individuals. The sites of infection are
the lung, nasal sinus, brain, eye, and skin. Infection may
have multiple sites.
mycelium
A mass of interwoven hyphae (a hypha is a filamentous part of a fungus that
usually has several cells in linear succession with dividing walls in between)
that is often submerged in soil or organic matter or the tissues of a host.
Myxomycetes
A taxonomic
designation for fungi that are included in the category of "slime
molds". They're occasionally found indoors, but mainly
reside in forested regions on decaying logs, stumps, and dead
leaves. Myxomycetes display characteristics of fungi and protozoans.
In favorable (wet) conditions they exhibit motile, amoeba-like
cells, usually bounded only by a plasma membrane, that are
variable in size and form. During dry spells, they form a resting
body (sclerotium) with dry, airborne spores. These fungi are
not known to produce toxins, but can cause hay fever and asthma.
Nigrospora
Commonly found in warm climates, this mold may be
responsible for allergic reactions such as hay fever and asthma.
It is found on decaying plant material and in the soil. It
is not often found indoors.
Oidium
The asexual phase of Erysiphe sp. It is a plant
pathogen causing powdery mildews. It is very common on the
leaves stems, and flowers of plants. The health effects and
allergenicity have not been studied. It does not grow on non-living
surfaces such as wood or drywall.
Paecilomyces
Commonly found in soil and dust; less frequently in air. P.
variotii can cause paecilomycosis. Linked to wood-trimmer's
disease and humidifier associated illnesses. They are reported
to allergenic. Some members of this genus are reported to cause
pneumonia. It may produce arsine gas if growing on arsenic
substrate. This can occur on wallpapers covered with Paris
green.
Papulospora
These fungi are found in soil, textiles, decaying plants, manure, and paper.
Penicillium
Aw 0.78 - 0.88. A wide number of organisms have been placed
in this genus. Identification to species is difficult. Often
found in aerosol samples. Commonly found in soil, food, cellulose
and grains. It is also found in paint and compost piles. It
may cause hypersensitivity pneumonitis, allergic alveolitis
in susceptible individuals. It is reported to be allergenic
(skin). It is commonly found in carpet, wallpaper, and in interior
fiberglass duct insulation. Some species can produce mycotoxins.
Common cause of extrinsic asthma (immediate-type hypersensitivity:
type I). Acute symptoms include edema and bronchiospasms; chronic
cases may develop pulmonary emphysema. It may also cause headaches,
vomiting, and diarrhea.
Periconia
Found in soil, blackened and dead herbaceous stems, leaf
spots, grasses, rushes, and sedges. Almost always associated
with other fungi. Rarely found growing indoors. Reportedly
associated with a rare case of mycotic keratitis.
perithecium
A fruiting body of a fungus in which some types of spores
(including ascospores) are produced. (plural form: perithecia)
Peronospora
These species are plant pathogens and the genus is one
that causes downy mildews. Peronospora is very common
and is an obligate parasite (obligate parasites cannot grow
on non living environmental surfaces) found on leaves, stems,
flowers, and fruits of living higher plants. Peronospora sp.
may be identified in air on spore trap samples since spores
have a distinctive morphology. The spores may also
be seen in dust as part of the normal influx of outdoor microbial
particles. As of this writing, allergenicity has not been studied
and no information is available regarding health effects or
toxicity.
phaeohyphomycosis
A hyphomycosis (infection by a mold of the taxonomic designation "Hyphomycetes")
in which the infiltrating microbes are usually of the mold family "Dematiaceae",
and are characterized by the coloring of their mycelium; the prefix "phaeo" means "dusky-brown".
Various forms of the disease involve different areas of the body, such as the
skin or respiratory tract. Intrusion of the mold in the eye, brain, bone, or
subcutaneous tissue typically occurs as a result of trauma to the affected
area.
Phoma
A common indoor air allergen that can cause hay fever,
asthma, and a type of hypersensitivity pneumonitis commonly
called "shower curtain disease" (shower surfaces
being among those frequented by this fungal organism). Phoma infections
in humans also have been reported; usually affecting the immunocompromised,
they include mycotic keratitis (fungal infection of the cornea),
skin infections, and phaeohyphomycosis (see phaeohyphomycosis).
For a positive identification of this genus, the specimen
must contain the pycnidia (a round to pear-shaped fruiting
structure containing conidia) to confirm the presence of simple
phialides (a cell from which conidia are extruded). A cultured
sample would provide these components. Colonies are rapid growing,
appear powdery to velvety, and exhibit many different colors.
This mold is known to grow on butter, rice, potatoes, paint
(sometimes seen as pink and purple spots on painted walls),
cement, rubber, wood, paper, and under linoleum. In nature,
the species are found in soil, manure, on fruit, dead plants,
and as parasites on live plants.
Researchers have discovered that when Phoma macrostoma is
sprinkled onto the soil in areas with no preexisting weeds,
it acts as an earth-friendly herbicide, inhibiting the ability
of many broadleaf plants (including dandelions) to produce
chlorophyll; the young broadleaf plants turn white and die
while grass seems to be unaffected.
Pithomyces
A native of mostly tropical environments, it commonly grows
on dead plants, soil, wood, and especially the dead leaves
and grasses of livestock fodder. Pithomyces chartarum produces
sporidesmin (a piperazinedione), a mycotoxin known to cause
animal liver damage, and it causes facial eczema in cattle,
sheep, and goats. For humans, it is considered a possible allergen,
and a potential infectious agent in immunocompromised patients.
Not known to be prolific indoors, this mold can sometimes be found on paper.
It exhibits distinctive multi-celled brown conidia.
Rhizomucor
The Zygomycetous fungus is reported to be allergenic. It
may cause mucorosis in immune compromised individuals. It occupies
a biological niche similar to Mucor sp. It is often
linked to occupational allergy. May cause mucorosis in immune
compromised individuals. The sites of infection are the lung,
nasal sinus, brain, eye, and skin. Infection may have multiple
sites.
Rhizopus
The Zygomycetous fungus is reported to be allergenic. It
may cause mucorosis in immune compromised individuals. It occupies
a biological niche similar to Mucor sp. It is often
linked to occupational allergy. May cause mucorosis in immune
compromised individuals. The sites of infection are the lung,
nasal sinus, brain, eye, and skin. Infection may have multiple
sites.
Rhodotorula
A reddish
yeast typically found in moist environments such as carpeting,
cooling coils, and drain pans. In some countries it is the
most common yeast genus identified in indoor air. This yeast
has been reported to be allergenic. Positive skin tests have
been reported. It has colonized terminally ill patients.
rusts (and
smuts)
These fungi are associated with plant diseases. In the classification scheme
of the fungi, the smuts have much in common with the rusts, and they are frequently
discussed together. Both groups produce wind-borne, resistant teliospores that
serve as the basis for their classification and their means of spread. Rusts
usually attack vegetative regions (i.e., leaves and stems) of plants; smuts
usually are associated with the reproductive structures (seeds). They can cause
hay fever and asthma.
Saccharomyces
Reported to be allergenic. Baker's yeast.
Scopulariopsis
It may produce arsine gas if growing on arsenic substrate.
This can occur on wallpapers covered with Paris green. It has
been found growing on a wide variety of materials including
house dust. It is associated with type III allergy.
Sepedonium
Most easily recognized by the spores, which are colorless
to yellow, spiny, round, 1-celled, and produced singly at the
ends of short filaments. Sometimes phialides of the Acremonium or Gabarnaudia type
may also occur. A few species of Mortierella, as well
as the human pathogen Histoplasma capsulatum, produce
spores resembling those of Sepedonium. Isolated from
soil, but most commonly parasitized mushrooms.
Serpula
lacrymans
Common cause of extrinsic asthma (immediate-type hypersensitivity:
type I). Acute symptoms include edema and bronchiospasms; chronic
cases may develop pulmonary emphysema.
smuts
See rusts.
Spegazzinia
This mitosporic fungus (spores develop by means of asexual cell division) is
included in the classification group "Hyphomycetes". At this time,
no information is available concerning Spegazzinia allergenicity
or toxicity. Spegazzinia spores can be identified in air samples
by their distinctive structure, and have the potential to produce a colony
within seven to ten days. Colonies are considered relatively slow growing,
and are brownish-black to black in color. This saprobe (deriving its nourishment
from nonliving or decaying organic matter) is most commonly found in warm-temperate
to tropical areas in soil and on dead leaves, stems, trees, and other various
kinds of plant debris.
spore
The means by which molds reproduce. Spores are microscopic (2-100 micrometers)
and various shapes. Distribution can be accomplished by a breeze, water droplet,
or a person or animal passing by. They can even be discharged by the mold
(usually under moist conditions or high humidity).
Sporobolomyces
Reported
to be allergenic.
Sporoschisma
A mitosporic fungal genus of the classification group "Hyphomycetes".
At this time, no information is available concerning Sporoschisma allergenicity
or toxicity. It is known to exist on wood and stems, and these
can be submerged in fresh water. Microscopic features include
quadriseptate spores, originating in an enclosed membrane.
Sporothrix
The species Sporothrix schenckii can cause sporotrichosis,
but usually only in individuals that are immune compromised.
Sporotrichosis is a chronic fungal infection that results when
the mold enters the body where the skin is damaged or via the
lungs. If it reaches the bloodstream, it can affect many other
parts of the body.
Sporotrichum
Reported
to be allergenic. Additionally, Sporotrichum pruinosum has
been observed in the respiratory secretions of some human patients,
indicating a possible ability to colonize the bronchopulmonary
pathways. This
genus does not cause sporotrichosis (see also Sporothrix,
for there is some taxonomic confusion between these two genera).
Rarely found in
cooler regions, Sporotrichum is prevalent in warm-temperate
and tropical zones, and grows (rapidly) on soils, decaying
plant matter, wet or rotting wood, grasses, and landscaping
mulch. Colonies may appear white, rosy-beige, or orange,
and have a velvety to granular texture.
Stachybotrys
Aw - 0.94 , optimum Aw ->0.98. Several strains of this
mold (S. atra, S. chartarum, and S. alternans are
synonymous) may produce macrocyclic trichothecenes (one of which
is Satratoxin H) that are poisonous by inhalation. These mycotoxins,
when present, are primarily associated with the mold's spores.
Individuals with chronic exposure to Stachybotrys's toxins reported
cold and flu symptoms, sore throats, diarrhea, headaches, fatigue, dermatitis,
hair loss, general malaise, and psychological depression. For infants, the
toxins create a vulnerability to a serious condition called pulmonary hemosiderosis
(bleeding in the lungs) where severe bleeding can result in coughing blood
or nosebleeds, and low grade bleeding can cause chronic coughs and congestion
with anemia. People who unknowingly handled material contaminated with this
mold described symptoms of cough, rhinitis, burning sensations of the mouth
and nasal passages, and cutaneous irritation at the point of contact, especially
in areas of abundant perspiration. The toxins produced by this mold will suppress
the immune system, affecting the lymphoid tissue and the bone marrow. Animals
injected with macrocyclic trichothecenes exhibited the following symptoms:
necrosis and hemorrhage within the brain, thymus, spleen, intestines, lung,
heart, lymph nodes, liver, and kidneys.
This is a dark-colored fungus that grows on building materials with a high
cellulose content and a low nitrogen content. It is slow growing when compared
to other common molds, and may not appear to compete well in their presence.
Yet, when moisture levels are high for prolonged periods, Stachybotrys may
gradually become the dominating genus (possibly because of its yield of mycotoxins,
which are believed to be directed against other molds and bacteria). This organism
is usually difficult to find in indoor air samples unless it is physically
disturbed, but when it does appear it is an alert to find the source, as it
will likely be found growing in abundance. Its spores--which can be found in
a gelatinous mass--will die readily after release, but are still allergenic
and can be toxigenic. Areas with a relative humidity above 55%, and are subject
to temperature fluctuations, are ideal for toxin production.
Stemphylium
This
genus is included in the taxonomic designation "Hyphomycetes".
It is a known
allergen, causing Type I allergies (examples: hay fever, asthma).
Phaeohyphomycotic sinusitis has been reported in connection
with this mold. (See phaeohyphomycosis.)
Existing
mainly in the temperate northern hemisphere, it can be found
in soil, moist wood or cellulose materials, on decomposing
plants, and as pathogens on living plants (leaf spots are
one example). Colonies grow rapidly, and appear velvety to
cottony in texture; coloring is light brown or olive green
to black. Though it is rare to find indoor colonization,
it has been found in dust that is transferred in from outside,
including dust on air filters.
Syncephalastrum
Can cause
a respiratory infection characterized by a solid intracaitary
fungal ball.
Torula
Found
outdoors in air, soil, on dead vegetation, wood, and grasses.
Also found indoors on cellulosic materials. Reported to be
allergenic and may cause hay fever and asthma.
Trichocladium
This is a widespread mitosporic (lacking a sexual state) fungus of the classification
group "Hyphomycetes". There is little information regarding toxicity
or allergenicity, but it is known to rarely be the causative agent for
human keratitis (infection of the cornea).
Various
species of this genus may be identified from indoor sampling
(one species in particular, Trichocladium uniseptatum, is
found regularly on indoor environmental surfaces, especially
wood). Outdoors, it is found on dead wood, stems or twigs,
tubers of various plants, pine needles, other plant debris,
and in soils. It is notable that this microbe has been associated
with black root rot, as an aggressive plant pathogen.
Trichoderma
It is commonly found in soil, dead trees, pine needles,
paper, and unglazed ceramics. It often will grow on other fungi.
It produces antibiotics that are toxic to humans. It has been
reported to be allergenic. It readily degrades cellulose.
Trichophyton
Can cause ringworm, athlete's foot, jock itch, and other
infections of the skin, nail, beard and scalp. Reported to
be allergenic. Found on soil and skin.
Trichothecium
Aw 0.90. Conidia dimensions: 12-23 x 8-10 microns. Found
in decomposing vegetation, soil, corn seeds, and in flour.
The species Trichothecium roseum can produce a trichothecene
toxin that may be associated with disease in humans and other
animals. Reported to be allergenic.
Tritirachium
Reported
to be allergenic.
Ulocladium
Aw 0.89. This mold is reported to be a major allergen,
capable of causing hay fever and asthma. It is also known to
rarely cause subcutaneous infections. The University of Adelaide,
Australia, categorizes this microbe in the classification group "Dematiaceous
Hyphomycetes", which includes it as a possible causative
agent of phaeohyphomycosis (see phaeohyphomycosis).
Widely
distributed in nature and considered a saprobe (weak parasite),
some of its growth sites are soil, grasses, dead or dying
plants (mainly herbaceous vegetation), manure, and compost.
In interior environments it has been found on paper, painted
surfaces, gypsum board, textiles, jute, straw materials,
carpets, cellulose building materials (including wood), and
in dust and air samples. Colonies are moderately fast growing,
usually appearing olive-brown (or rusty-brown) to black (or
grayish), with a texture that is granular to velvety.
Verticillium
Conidia
dimensions: 2.3-10 x 1-2.6 microns. Found in decaying vegetation,
on straw, soil and arthropods. A rare cause of corneal infections.
Wallemia
Aw 0.75.
Conidia dimensions: 2.5-3.5 microns. Found in sugary foods,
salted meats, dairy products, textiles, soil, hay and fruits.
yeast
Various
yeasts are commonly identified on air samples. Some yeasts
are reported to be allergenic. They may cause problems if a
person has had previous exposure and developed a hypersensitivity.
Yeasts may be allergenic to susceptible individuals when present
in sufficient concentrations.
~
"Aw" refers
to the water activity measurement, where Aw is
equal to the relative humidity of the air surrounding the
sample when the air and the sample are at equilibrium (in
an enclosed space).
For
help in finding word definitions:
http://ppathw3.cals.cornell.edu/glossary/Glossary.htm , "On-Line
Glossary of Technical Terms in Plant
Pathology", provided by Cornell
University.
For
additional information:
http://www.aerotechlabs.com/Infobase/resource.aspx?CatID=1 , "Microbial
Glossary", provided by Aerotech
Laboratories, Inc.
http://www.emlab.com/app/fungi/Fungi.po , "An
Index of Some Commonly Encountered Fungal Genera", provided
by Environmental Microbiology Laboratory, Inc.
http://www.dehs.umn.edu/iaq_fib_fg_gloss.htm , "Fungal
Glossary", provided by the University of Minnesota Department
of Environmental Health and Safety.
http://www.doctorfungus.org/thefungi/description_index.htm , "Fungi
Descriptions", provided by the DoctorFungus Corporation.
http://www.mercksource.com/ (abbreviated
URL), "Dorland's Medical Dictionary", provided
by W. B. Saunders.
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